Bench 2 Breakthrough Podcast Episode 5 - Bringing Innovation Closer to Patients: Rethinking Early-Phase Oncology Research

Bringing Innovation Closer to Patients: Rethinking Early-Phase Oncology Research

In this episode of the Bench to Breakthrough Podcast, host Greg Plunkett sits down with Scott Schliebner, CEO of P1 Pratia Oncology, to explore how community-based research networks are transforming the delivery of early-phase oncology clinical trials.

Drawing on more than three decades of experience in oncology drug development, Scott shares insights into the evolving clinical trial landscape, the importance of reducing barriers to patient access, and how innovative site network models can accelerate study start-up, improve operational efficiency, and bring cutting-edge therapies closer to the patients who need them most.

The discussion also examines key industry trends emerging from the recent BIO International Convention, including global clinical trial geography, investment pressures facing biotech companies, the future of immuno-oncology, and the growing importance of patient-centric trial design. Throughout the conversation, a consistent theme emerges: successful drug development depends on collaboration, speed, scientific excellence, and an unwavering focus on patient outcomes.

The episode discusses

  • The changing global landscape for clinical trial execution and why sponsors are increasingly looking beyond traditional markets.
  • Building a community-based Phase I oncology network and accelerating trial start-up timelines.
  • The role of site networks in improving operational efficiency and patient access.
  • Why patient-centric trial design remains one of the industry's greatest opportunities for improvement.
  • Challenges facing emerging biotech companies as they balance funding constraints with long-term development planning.
  • Emerging areas of excitement in oncology, including T-cell engagers, novel checkpoint targets, KRAS inhibitors, cell therapies, and next-generation immuno-oncology approaches.
  • How greater collaboration between sponsors, CROs, investigators, and patients can accelerate the path from discovery to treatment.

Whether you're a biotech founder, clinical development leader, investor, researcher, or healthcare professional, this episode offers valuable perspectives on the future of oncology drug development and the innovations helping bring new therapies to patients faster.

📻‍ Click here to listen now to discover how patient-focused innovation, operational excellence, and global collaboration are reshaping the next generation of cancer research.

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